Brain tumors in Li-Fraumeni syndrome: a commentary and a case of a gliosarcoma patient

Future Oncol. 2017 Jan;13(1):9-12. doi: 10.2217/fon-2016-0236. Epub 2016 Aug 15.

Authors

Milena Guidi¹, Laura Giunti², Maurizio Lucchesi¹, Silvia Scoccianti³, Sabrina Giglio², Claudio Favre¹, Giuseppe Oliveri⁴, Iacopo Sardi¹

Affiliations

¹ Neuro-Oncology Unit, Department of Pediatric Oncology, Meyer Children's University Hospital, Florence, Italy.
² Medical Genetics Unit, Meyer Children's University Hospital, Florence, Italy.
³ Radiation Oncology Unit, Azienda Universitaria Ospedaliera Careggi, Florence, Italy.
⁴ Department of Neurosurgery, Policlinico 'Santa Maria alle Scotte', Siena, Italy.

PMID: 27523101
DOI: 10.2217/fon-2016-0236

No abstract available

Keywords: Li-Fraumeni syndrome; TP53; gliosarcoma.

Publication types

Case Reports
Review

MeSH terms

Adolescent
Brain Neoplasms / diagnosis
Brain Neoplasms / etiology*
Brain Neoplasms / therapy
Combined Modality Therapy
Female
Gliosarcoma / etiology*
Humans
Li-Fraumeni Syndrome / complications*
Li-Fraumeni Syndrome / genetics
Magnetic Resonance Imaging
Mutation
Treatment Outcome
Tumor Suppressor Protein p53 / genetics

Substances

Tumor Suppressor Protein p53