Perinatal Asphyxia from the Obstetric Standpoint: Diagnosis and Interventions

Clin Perinatol. 2016 Sep;43(3):423-38. doi: 10.1016/j.clp.2016.04.003. Epub 2016 Jun 17.

Abstract

Perinatal asphyxia is a general term referring to neonatal encephalopathy related to events during birth. Asphyxia refers to a deprivation of oxygen for a duration sufficient to cause neurologic injury. Most cases of perinatal asphyxia are not necessarily caused by intrapartum events but rather associated with underlying chronic maternal or fetal conditions. Of intrapartum causes, obstetric emergencies are the most common and are not always preventable. Screening high-risk pregnancies with ultrasound, Doppler velocimetry, and antenatal testing can aid in identifying fetuses at risk. Interventions such as intrauterine resuscitation or operative delivery may decrease the risk of severe hypoxia from intrauterine insults and improve long-term neurologic outcomes.

Keywords: Birth asphyxia; Cerebral palsy; Hypoxic ischemic encephalopathy; Neonatal encephalopathy; Perinatal asphyxia.

Publication types

  • Review

MeSH terms

  • Abruptio Placentae / diagnosis
  • Abruptio Placentae / therapy
  • Asphyxia Neonatorum / prevention & control*
  • Cesarean Section
  • Emergencies
  • Female
  • Fetal Hypoxia / diagnosis*
  • Fetal Hypoxia / therapy
  • Humans
  • Hypoxia, Brain / prevention & control*
  • Infant, Newborn
  • Laser-Doppler Flowmetry
  • Mass Screening
  • Obstetrics
  • Pregnancy
  • Pregnancy, High-Risk
  • Resuscitation
  • Risk Assessment*
  • Ultrasonography, Prenatal
  • Umbilical Cord
  • Uterine Rupture / diagnosis
  • Uterine Rupture / therapy