Estrogen-Mediated Activation of H875Y Androgen Receptor Mutation in a Prostate Cancer Patient

Clin Genitourin Cancer. 2017 Feb;15(1):e111-e113. doi: 10.1016/j.clgc.2016.07.015. Epub 2016 Jul 22.

Authors

Ashwin K Vasudevamurthy¹, Elisa Ledet², Cathryn Garvey², Brian E Lewis³, Oliver Sartor²

Affiliations

¹ Section of Hematology/Medical Oncology, Tulane University School of Medicine, New Orleans, LA. Electronic address: [email protected].
² Department of Medicine and Urology, Tulane Cancer Center, Tulane University School of Medicine, New Orleans, LA.
³ Section of Hematology/Medical Oncology, Tulane University School of Medicine, New Orleans, LA.

PMID: 27527401
DOI: 10.1016/j.clgc.2016.07.015

No abstract available

Keywords: Castration-resistant prostate cancer; Estrogen; PSA; Withdrawal response; cfDNA.

Publication types

Case Reports

MeSH terms

Benzamides
Cell-Free Nucleic Acids / genetics
Drug Resistance, Neoplasm
Estrogens / administration & dosage
Estrogens / therapeutic use
Humans
Male
Middle Aged
Mutation*
Nitriles
Phenylthiohydantoin / administration & dosage
Phenylthiohydantoin / analogs & derivatives
Phenylthiohydantoin / therapeutic use
Prostatic Neoplasms / drug therapy*
Prostatic Neoplasms / genetics
Receptors, Androgen / genetics*
Sequence Analysis, DNA / methods*

Substances

AR protein, human
Benzamides
Cell-Free Nucleic Acids
Estrogens
Nitriles
Receptors, Androgen
Phenylthiohydantoin
enzalutamide