Reduced frequency of circulating CD4+CD25brightCD127lowFOXP3+ regulatory T cells in primary myelofibrosis

Blood. 2016 Sep 22;128(12):1660-2. doi: 10.1182/blood-2016-03-704577. Epub 2016 Aug 16.

Affiliations

¹ Biotechnology Research Area.
² Center for the Study of Myelofibrosis, Biotechnology Research Area.
³ Immunohematology and Transfusion Service, and.
⁴ Division of Pediatrics, Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo Foundation, Pavia, Italy; and.
⁵ Haematology Research Centre, Division of Haematology, Department of Medicine, Imperial College London, London, United Kingdom.

PMID: 27531678
DOI: 10.1182/blood-2016-03-704577

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

CD4 Lymphocyte Count
CD4-Positive T-Lymphocytes / metabolism
CD4-Positive T-Lymphocytes / pathology*
Case-Control Studies
Cross-Sectional Studies
Female
Forkhead Transcription Factors / metabolism
Humans
Interleukin-2 Receptor alpha Subunit / metabolism
Interleukin-7 Receptor alpha Subunit / metabolism
Male
Primary Myelofibrosis / blood*
Primary Myelofibrosis / immunology
Primary Myelofibrosis / pathology
T-Lymphocytes, Regulatory / metabolism
T-Lymphocytes, Regulatory / pathology*

Substances

FOXP3 protein, human
Forkhead Transcription Factors
IL2RA protein, human
Interleukin-2 Receptor alpha Subunit
Interleukin-7 Receptor alpha Subunit