Effective ADAPT Thrombectomy in a Patient with Acute Stroke due to Cardiac Papillary Elastofibroma: Histological Thrombus Confirmation

J Stroke Cerebrovasc Dis. 2016 Oct;25(10):e185-7. doi: 10.1016/j.jstrokecerebrovasdis.2016.07.026. Epub 2016 Aug 15.

Abstract

A 75-year-old man with hypertension and atrial fibrillation was admitted to our emergency room with right-sided hemiplegia and complete aphasia (National Institutes of Health Stroke Scale [NIHSS] score = 18). A noncontrast computed tomography scan showed a slight hypodensity in the left insular region and a bright hyperdense sign in the M1 tract of the left middle cerebral artery (MCA). Angio-CT confirmed an occlusion of the M1 tract of the MCA. Magnetic resonance diffusion-weighted imaging/perfusion-weighted imaging was obtained and revealed a mismatch in the left parietal cortical region. Complete revascularization was achieved by thromboaspiration with the A Direct ASPIRATION first PASS TECHNIQUE (ADAPT) technique. Histological examination of the embolic material revealed its nonthrombotic nature: cardiac embolic papillary elastofibroma (PEF). At discharge, good recovery of right-side hemiplegia was observed. This case report is the second in literature in which a histological confirmed cardiac embolic PEF is reported as a cause of embolic stroke. PEF is a rare but potentially treatable cause of embolic stroke. Understanding the nature of the embolic material would help in choosing the best revascularization approach.

Keywords: ADAPT; MR perfusion; Stroke; cardiac embolism; mechanical thrombectomy; papillary elastofibroma; thrombus.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cerebral Angiography / methods
  • Computed Tomography Angiography
  • Diffusion Magnetic Resonance Imaging
  • Fibroma / complications*
  • Fibroma / pathology
  • Heart Neoplasms / complications*
  • Heart Neoplasms / pathology
  • Humans
  • Infarction, Middle Cerebral Artery / diagnostic imaging
  • Infarction, Middle Cerebral Artery / etiology
  • Infarction, Middle Cerebral Artery / therapy*
  • Intracranial Embolism / diagnostic imaging
  • Intracranial Embolism / etiology
  • Intracranial Embolism / therapy*
  • Male
  • Neoplastic Cells, Circulating / pathology*
  • Perfusion Imaging
  • Thrombectomy / methods*
  • Treatment Outcome