[Why a hydroxyapatite cranioplasty can be used to repair a cranial bone defect in children: Experience of 19 cases]

Neurochirurgie. 2016 Oct;62(5):251-257. doi: 10.1016/j.neuchi.2016.04.003. Epub 2016 Aug 17.
[Article in French]

Abstract

Introduction: The use of an autologous bone graft to repair a cranial bone defect is sometimes impossible in pediatric cases. CUSTOMBONE® made with hydroxyapatite is a good alternative in these indications for neurosurgeons.

Material and methods: We present a pediatric series of 19 children who benefited from a cranioplasty using CUSTOMBONE®. Their ages ranged between 8 months and 13 years with a mean of 6 years and 2 months. The most frequent indication was a cranioplasty after a post-traumatic decompressive craniectomy.

Results: No complications were reported. Cosmetic outcome was satisfactory in all patients. Only one plasty needed to be changed after a severe head trauma during the postoperative period. The assessment of cerebral blood flow was improved in all patients postoperatively. Complete ossification of the plasty is a long process. The mean time for the ossification to begin was 13 months (range: 3-22 months). The mean follow-up was 2.7 years.

Discussion: The excellent integration of the prosthesis is related to the accuracy of the reconstruction of the preoperative model. The minimum thickness of the plasty (4mm) could represent a challenge in very young children. One limitation is the cost, which remains high.

Conclusion: CUSTOMBONE® met the criteria of protection and restoration of the normal intracranial physiology with good cosmetic results, which are necessary qualities for excellent clinical outcome.

Keywords: Bone defect; Cranioplasty; Hydroxyapatite; Pediatric; Perte de substance osseuse; Plastie crânienne; Pédiatrie.

MeSH terms

  • Adolescent
  • Bone Transplantation / methods
  • Child
  • Child, Preschool
  • Craniocerebral Trauma / surgery*
  • Decompressive Craniectomy / methods
  • Durapatite / therapeutic use*
  • Female
  • Humans
  • Infant
  • Male
  • Plastic Surgery Procedures* / methods
  • Skull / surgery*
  • Transplantation, Autologous / methods
  • Treatment Outcome

Substances

  • Durapatite