Optimized Protocol for Fast CT Angiography of Lower Limbs Using 160-Row Detector

J Comput Assist Tomogr. 2016 Nov/Dec;40(6):953-957. doi: 10.1097/RCT.0000000000000459.

Abstract

Objective: We proposed and tested a novel acquisition protocol for optimizing a fast computed tomography angiography using a 160-row detector scanner using a longer contrast injection time coupled with multiphasic rate of injection.

Methods: A prospective randomized study was performed to compare image quality, contrast enhancement, and radiation dose in 2 groups (a fast acquisition and a widely accepted slow acquisition).

Results: There was no difference between groups regarding image quality, noise, and diagnostic performance, but we evidenced a trend to higher radiation dose for the fast acquisition protocol.

Conclusions: An optimized protocol for performing a fast acquisition computed tomography angiography of lower limbs is feasible, has sufficient diagnostic quality, and can be used in selected patients who would benefit from a short-time scan.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Algorithms
  • Arteries / diagnostic imaging*
  • Computed Tomography Angiography / methods*
  • Contrast Media / administration & dosage
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Injections, Intravenous
  • Iohexol / administration & dosage
  • Iohexol / analogs & derivatives*
  • Lower Extremity / blood supply*
  • Male
  • Middle Aged
  • Multidetector Computed Tomography / methods*
  • Radiographic Image Enhancement / methods*
  • Radiographic Image Interpretation, Computer-Assisted / methods
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Young Adult

Substances

  • Contrast Media
  • iobitridol
  • Iohexol