Modeling of Experimental Data Supports HIV Reactivation from Latency after Treatment Interruption on Average Once Every 5-8 Days

Mykola Pinkevych; Stephen J Kent; Martin Tolstrup; Sharon R Lewin; David A Cooper; Ole S Søgaard; Thomas A Rasmussen; Anthony D Kelleher; Deborah Cromer; Miles P Davenport

doi:10.1371/journal.ppat.1005740

Modeling of Experimental Data Supports HIV Reactivation from Latency after Treatment Interruption on Average Once Every 5-8 Days

PLoS Pathog. 2016 Aug 25;12(8):e1005740. doi: 10.1371/journal.ppat.1005740. eCollection 2016 Aug.

Authors

Mykola Pinkevych¹, Stephen J Kent^{2

3

4}, Martin Tolstrup⁵, Sharon R Lewin^{3

4}, David A Cooper¹, Ole S Søgaard⁵, Thomas A Rasmussen^{3

5}, Anthony D Kelleher¹, Deborah Cromer¹, Miles P Davenport¹

Affiliations

¹ Kirby Institute for Infection and Immunity, UNSW Australia, Sydney, Australia.
² Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Australia.
³ The Peter Doherty Institute for Infection and Immunity, The University of Melbourne and Royal Melbourne Hospital, Melbourne, Australia.
⁴ Department of Infectious Diseases, Alfred Hospital and Monash University, Melbourne, Australia.
⁵ Department of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

HIV-1*
Virus Latency*

Grants and funding

This work was funded by a Australian National Health and Medical Research Council (NHMRC) Program Grant (1052979, to MPD, ADK, SJK, DAC, and SRL), http://www.nhmrc.gov.au/; NHMRC Fellowships to MPD (630 542), SJK (1041832), SRL (1042654), and ADK (10220536); and by the Danish Council for Independent Research (OSS), http://ufm.dk/en/. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.