Two cases of neonatal group B streptococcal (GBS) infection occurring in a large consanguineous kindred are described. The observation suggests that susceptibility to isolated GBS disease in this family may have been the result of an inborn error of immunity inherited as a Mendelian autosomal recessive trait.
Keywords: GBS; Genetic; Mendelian; Neonatal; Primary immunodeficiency; Streptococcus agalactiae.
Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.