Orbital peripheral nerve sheath tumors

Adam R Sweeney; Divakar Gupta; C Dirk Keene; Patrick J Cimino; Christopher B Chambers; Shu-Hong Chang; Eissa Hanna

doi:10.1016/j.survophthal.2016.08.002

Orbital peripheral nerve sheath tumors

Surv Ophthalmol. 2017 Jan-Feb;62(1):43-57. doi: 10.1016/j.survophthal.2016.08.002. Epub 2016 Aug 26.

Authors

Adam R Sweeney¹, Divakar Gupta², C Dirk Keene³, Patrick J Cimino³, Christopher B Chambers⁴, Shu-Hong Chang⁴, Eissa Hanna⁴

Affiliations

¹ Department of Ophthalmology, University of Washington, Seattle, Washington, USA. Electronic address: [email protected].
² Department of Ophthalmology, Duke University, Durham, North Carolina, USA.
³ Department of Pathology, University of Washington, Seattle, Washington, USA.
⁴ Department of Ophthalmology, University of Washington, Seattle, Washington, USA.

PMID: 27570221
DOI: 10.1016/j.survophthal.2016.08.002

Abstract

Peripheral nerve sheath tumors of the orbit and ocular adnexa are a rare group of neoplasms hallmarked by nonspecific clinical presentations, variable tumor locations, challenging therapeutic efforts, and occasional diagnostic dilemmas. We review these tumor types and provide an updated summary on their clinical, histopathologic, radiological, and emerging molecular features.

Keywords: histology; magnetic resonance imaging; malignant; neurilemmoma; neurinoma; neurofibroma; neurofibromatosis; pathology; peripheral nerve sheath tumor; schwannoma.

Publication types

Review

MeSH terms

Diagnosis, Differential
Global Health
Humans
Magnetic Resonance Imaging
Morbidity
Nerve Sheath Neoplasms* / diagnosis
Nerve Sheath Neoplasms* / epidemiology
Nerve Sheath Neoplasms* / surgery
Ophthalmologic Surgical Procedures / methods*
Orbital Neoplasms* / diagnosis
Orbital Neoplasms* / epidemiology
Orbital Neoplasms* / surgery
Tomography, X-Ray Computed