Cyst Fluid Analysis in Pancreatic Intraductal Papillary Mucinous Neoplasms

Clin Cancer Res. 2016 Oct 15;22(20):4966-4967. doi: 10.1158/1078-0432.CCR-16-1462. Epub 2016 Aug 29.

Abstract

Pancreatic intraductal papillary mucinous neoplasms (IPMN) are surgically treatable cancer precursors, if high-risk features can be identified. Analysis of proteins and genes in cyst fluid helps diagnostically, but prior biomarkers had limited ability to detect high-risk cases. Cyst fluid telomerase activity may be a useful biomarker for high-risk IPMNs. Clin Cancer Res; 22(20); 4966-7. ©2016 AACRSee related article by Hata et al., p. 5141.

MeSH terms

  • Adenocarcinoma, Mucinous / diagnosis
  • Adenocarcinoma, Mucinous / pathology*
  • Biomarkers, Tumor / metabolism
  • Carcinoma, Pancreatic Ductal / diagnosis
  • Carcinoma, Pancreatic Ductal / pathology*
  • Cyst Fluid / metabolism*
  • Humans
  • Pancreatic Cyst / metabolism*
  • Pancreatic Ducts / pathology
  • Pancreatic Ducts / surgery
  • Pancreatic Neoplasms / diagnosis
  • Pancreatic Neoplasms / pathology*
  • Telomerase / metabolism*

Substances

  • Biomarkers, Tumor
  • Telomerase