Canangalias C-H, juvenile hormone III analogues from the roots of Cananga latifolia

Ratchanee Phatchana; Yordhathai Thongsri; Chavi Yenjai

doi:10.1016/j.fitote.2016.08.018

Canangalias C-H, juvenile hormone III analogues from the roots of Cananga latifolia

Fitoterapia. 2016 Oct:114:45-50. doi: 10.1016/j.fitote.2016.08.018. Epub 2016 Aug 26.

Authors

Ratchanee Phatchana¹, Yordhathai Thongsri², Chavi Yenjai³

Affiliations

¹ Natural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
² Cellular and Molecular Immunology Research Unit, Department of Medical Technology, Faculty of Allied Health Science, Naresuan University, Phitsanulok 65000, Thailand.
³ Natural Products Research Unit, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address: [email protected].

PMID: 27575324
DOI: 10.1016/j.fitote.2016.08.018

Abstract

Chemical investigation of the roots of Cananga latifolia led to the isolation and purification of thirteen juvenile hormone III analogues. Six new analogues, canangalias C-H (1-6) and a new natural product, (2E,6E,10R)-10-acetoxy-11-hydroxy-3,7,11-trimethyldodeca-2,6-dienoic acid methyl ester (7), were isolated. In addition, six known juvenile hormone III analogues were isolated. Their structures were established by spectroscopic methods including 1D and 2D NMR, IR and mass spectrometry.

Keywords: Annonaceae; Cananga latifolia; Canangalias; Juvenile hormone III; Sesquiterpenes.

MeSH terms

Antifungal Agents / chemistry
Antifungal Agents / isolation & purification
Cananga / chemistry*
Magnetic Resonance Spectroscopy
Mass Spectrometry
Molecular Structure
Phytochemicals / chemistry*
Phytochemicals / isolation & purification
Plant Roots / chemistry*
Pythium / drug effects
Sesquiterpenes / chemistry*
Sesquiterpenes / isolation & purification

Substances

Antifungal Agents
Phytochemicals
Sesquiterpenes
juvenile hormone III