Air pollutant-mediated disruption of sinonasal epithelial cell barrier function is reversed by activation of the Nrf2 pathway

J Allergy Clin Immunol. 2016 Dec;138(6):1736-1738.e4. doi: 10.1016/j.jaci.2016.06.027. Epub 2016 Jul 27.

Authors

Nyall R London Jr¹, Anuj Tharakan¹, Ana M Rule², Andrew P Lane¹, Shyam Biswal², Murugappan Ramanathan Jr³

Affiliations

¹ Johns Hopkins Department of Otolaryngology-Head and Neck Surgery, Baltimore, Md.
² Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Md.
³ Johns Hopkins Department of Otolaryngology-Head and Neck Surgery, Baltimore, Md. Electronic address: [email protected].

PMID: 27576127
DOI: 10.1016/j.jaci.2016.06.027

No abstract available

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Air Pollutants / adverse effects*
Air Pollution / adverse effects*
Animals
Epithelial Cells / drug effects*
Epithelial Cells / metabolism*
Humans
NF-E2-Related Factor 2 / metabolism*
Particulate Matter / adverse effects
Zonula Occludens-1 Protein / metabolism

Substances

Air Pollutants
NF-E2-Related Factor 2
Particulate Matter
Zonula Occludens-1 Protein