OCT angiography in the management of choroidal neovascular membrane secondary to Sorsby fundus dystrophy

BMJ Case Rep. 2016 Sep 1:2016:bcr2016216453. doi: 10.1136/bcr-2016-216453.

Abstract

We describe the management of a woman aged 52 years with molecularly confirmed Sorsby fundus dystrophy, who presented with acute visual deterioration in her right eye. Fundus examination identified a right macular lesion suggestive of a choroidal neovascular membrane (CNVM). Optical coherence tomography angiography (OCTA) confirmed the presence of a CNVM. She was treated with 2 monthly intravitreal injections of bevacizumab, associated with OCTA evidence of regression of the CNVM and improvement in her visual acuity. OCTA is a novel, non-invasive method of imaging the retinal vasculature. Images are acquired rapidly, with no associated side effects, offering advantages over the current gold standard technique-fundus fluorescein angiography.

Publication types

  • Case Reports

MeSH terms

  • Angiogenesis Inhibitors / therapeutic use
  • Bevacizumab / therapeutic use
  • Choroid / blood supply
  • Choroid / diagnostic imaging*
  • Choroid / pathology
  • Choroidal Neovascularization / diagnosis
  • Choroidal Neovascularization / diagnostic imaging*
  • Choroidal Neovascularization / drug therapy
  • Choroidal Neovascularization / etiology
  • Female
  • Fluorescein Angiography
  • Humans
  • Macular Degeneration / complications*
  • Middle Aged
  • Tomography, Optical Coherence*
  • Vision Disorders / diagnosis
  • Vision Disorders / diagnostic imaging*
  • Vision Disorders / drug therapy
  • Vision Disorders / etiology
  • Visual Acuity*

Substances

  • Angiogenesis Inhibitors
  • Bevacizumab

Supplementary concepts

  • Fundus Dystrophy, Pseudoinflammatory, Of Sorsby