Signaling a link between interferon and the traits of Down syndrome

Elife. 2016 Sep 6:5:e20196. doi: 10.7554/eLife.20196.

Abstract

Elevated interferon signaling is a hallmark of Down syndrome.

Keywords: JAK inhibitors; chromosomes; down syndrome; genes; human; human biology; interferon; medicine; mouse; ruxolitinib; trisomy 21.

Publication types

  • Comment

MeSH terms

  • Down Syndrome*
  • Humans
  • Interferons
  • Phenotype
  • Signal Transduction
  • Trisomy

Substances

  • Interferons