Complete Response to Aflibercept-FOLFIRI in One Patient With Colorectal Cancer Refractory to Bevacizumab-FOLFOX: A Possible Autocrine Vascular Endothelial Growth Factor Receptor 2-Related Mechanism

MeSH terms

• Angiogenesis Inhibitors / adverse effects
• Angiogenesis Inhibitors / therapeutic use*
• Antineoplastic Combined Chemotherapy Protocols / adverse effects
• Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
• Bevacizumab / adverse effects*
• Bevacizumab / therapeutic use
• Camptothecin / analogs & derivatives*
• Camptothecin / therapeutic use
• Colorectal Neoplasms / drug therapy*
• Colorectal Neoplasms / metabolism
• Colorectal Neoplasms / pathology
• Drug Resistance, Neoplasm / genetics
• Fluorouracil / adverse effects
• Fluorouracil / therapeutic use
• Humans
• Leucovorin / adverse effects
• Leucovorin / therapeutic use
• Male
• Middle Aged
• Organoplatinum Compounds / adverse effects
• Organoplatinum Compounds / therapeutic use
• Receptors, Vascular Endothelial Growth Factor / therapeutic use*
• Recombinant Fusion Proteins / therapeutic use*
• Tomography, X-Ray Computed
• Treatment Outcome
• Vascular Endothelial Growth Factor Receptor-2 / metabolism*