A tentative interpretation of the TOPCAT trial based on randomized evidence from the brain natriuretic peptide stratum analysis

Eur J Heart Fail. 2016 Dec;18(12):1411-1414. doi: 10.1002/ejhf.621. Epub 2016 Sep 9.

Authors

Nicolas Girerd¹, João Pedro Ferreira^{1

2}, Patrick Rossignol¹, Faiez Zannad¹

Affiliations

¹ INSERM, Centre d'Investigations Cliniques Plurithématique 1433, INSERM U1116, Université de Lorraine, CHRU de Nancy, F-CRIN INI-CRCT, Nancy, France.
² Department of Physiology and Cardiothoracic Surgery, Cardiovascular Research and Development Unit, Faculty of Medicine, University of Porto, Porto, Portugal.

PMID: 27612005
DOI: 10.1002/ejhf.621

No abstract available

Keywords: BNP stratum; Heart failure; Randomized evidence; Spironolactone; TOPCAT trial; interaction.

Publication types

Comment

MeSH terms

Heart Failure*
Humans
Mineralocorticoid Receptor Antagonists
Natriuretic Peptide, Brain*
Spironolactone

Substances

Mineralocorticoid Receptor Antagonists
Natriuretic Peptide, Brain
Spironolactone