RETRACTED: Low density lipoprotein receptor targeted doxorubicin/DNA-Gold Nanorods as a chemo- and thermo-dual therapy for prostate cancer

Int J Pharm. 2016 Nov 20;513(1-2):376-386. doi: 10.1016/j.ijpharm.2016.09.002. Epub 2016 Sep 6.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the authors and sanctioned by the Editor-in-Chief. The authors found errors in the data presentation - apoptotic statistics and in vivo distribution - which makes the conclusion not representative. The authors express sincere apologies for the error and inconvenience to readers.

Keywords: Chemotherapy; Doxorubicin; Gold nanorods; Low density lipoprotein peptide; Prostate cancer; Thermotherapy.

Publication types

  • Retracted Publication

MeSH terms

  • Animals
  • Antineoplastic Agents / administration & dosage*
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / therapeutic use
  • Apoptosis / drug effects
  • Cell Line, Tumor
  • Cell Survival / drug effects
  • Combined Modality Therapy
  • DNA Adducts / administration & dosage*
  • DNA Adducts / chemistry
  • DNA Adducts / therapeutic use
  • Doxorubicin / administration & dosage*
  • Doxorubicin / chemistry
  • Doxorubicin / therapeutic use
  • Drug Carriers / administration & dosage*
  • Drug Carriers / chemistry
  • Drug Carriers / therapeutic use
  • Gold / administration & dosage*
  • Gold / chemistry
  • Gold / therapeutic use
  • Humans
  • Hyperthermia, Induced
  • Male
  • Mice, Inbred BALB C
  • Mice, Nude
  • Nanotubes* / chemistry
  • Peptides / chemistry
  • Polyethylene Glycols / chemistry
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / therapy*
  • Receptors, LDL / metabolism*
  • Tumor Burden / drug effects

Substances

  • Antineoplastic Agents
  • DNA Adducts
  • Drug Carriers
  • Peptides
  • RLT peptide
  • Receptors, LDL
  • doxorubicin-DNA
  • Polyethylene Glycols
  • Gold
  • Doxorubicin