Abstract
Using in vivo dialysis in the A10 region of the anesthetized rat, somatodendritic release of endogenous dopamine was demonstrated. Although endogenous dopamine release from the A10 region was enhanced by amphetamine pretreatment in a dose-related manner, the amount of dopamine released was markedly less than the axonal release of dopamine measured simultaneously in the nucleus accumbens.
Publication types
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
3,4-Dihydroxyphenylacetic Acid / metabolism
-
Amphetamines / pharmacology
-
Animals
-
Corpus Striatum / drug effects
-
Corpus Striatum / metabolism*
-
Dendrites / drug effects
-
Dendrites / metabolism*
-
Dopamine / metabolism*
-
Homovanillic Acid / metabolism
-
In Vitro Techniques
-
Male
-
Nucleus Accumbens / drug effects
-
Nucleus Accumbens / metabolism
-
Rats
-
Rats, Inbred Strains
-
Substantia Nigra / drug effects
-
Substantia Nigra / metabolism*
Substances
-
Amphetamines
-
3,4-Dihydroxyphenylacetic Acid
-
Dopamine
-
Homovanillic Acid