[Cytology of cerebrospinal fluid : Standards, importance and modern methods]

Nervenarzt. 2016 Dec;87(12):1276-1281. doi: 10.1007/s00115-016-0219-5.
[Article in German]

Abstract

Cytology is an integral part of cerebrospinal fluid (CSF) analysis. It is relevant for the diagnostics and differential diagnosis of inflammatory, hemorrhagic and neoplastic central nervous system (CNS) processes. This article summarizes the recommended procedures and typical clinical patterns. In addition, modern immunocytochemical and flow cytometry methods for CSF cytology are presented. In particular, the diagnostic contribution and clinical relevance in several CNS conditions are discussed.

Keywords: Cytometry; Immunophenotyping; Meningitis; Multiple sclerosis; Neoplastic processes.

Publication types

  • Review

MeSH terms

  • Biomarkers
  • Brain Diseases / cerebrospinal fluid*
  • Brain Diseases / diagnosis*
  • Brain Diseases / pathology
  • Cerebrospinal Fluid / cytology*
  • Flow Cytometry / methods*
  • Humans
  • Immunohistochemistry / methods*
  • Immunophenotyping / methods*

Substances

  • Biomarkers