Neuroprotection during aortic surgery

Helen Lindsay; Coimbatore Srinivas; George Djaiani

doi:10.1016/j.bpa.2016.05.002

Neuroprotection during aortic surgery

Best Pract Res Clin Anaesthesiol. 2016 Sep;30(3):283-303. doi: 10.1016/j.bpa.2016.05.002. Epub 2016 May 14.

Authors

Helen Lindsay¹, Coimbatore Srinivas², George Djaiani³

Affiliations

¹ Department of Anesthesia & Pain Management, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address: [email protected].
² Department of Anesthesia & Pain Management, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address: [email protected].
³ Department of Anesthesia & Pain Management, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address: [email protected].

PMID: 27650340
DOI: 10.1016/j.bpa.2016.05.002

Abstract

Neurological injury is a major limitation of aortic surgery, whether it involves spinal cord injury following intervention to the thoracoabdominal aorta, or stroke following surgery on the arch and ascending aorta. Despite an extensive body of literature and various proposals, a completely effective strategy to prevent or treat neurological injury remains elusive. In this article, we summarise the evidence for established and emerging strategies, and review current concepts in pathophysiology and risk assessment as they relate to neurological injury.

Keywords: aortic surgery; neurologic injury; neuromonitoring; neuroprotection; risk factors; spinal cord injury; stroke; temporary neurological dysfunction.

Publication types

Review

MeSH terms

Aorta / surgery*
General Surgery / standards
Humans
Neuroprotection*
Risk Factors
Spinal Cord Injuries / prevention & control*