Detection of clonal heterogeneity and targetable mutations in myeloid sarcoma by high-throughput sequencing

Cedric Pastoret; Roch Houot; Francisco Llamas-Gutierrez; Marie-Laure Boulland; Tony Marchand; Patrick Tas; Beatrice Ly-Sunnaram; Virginie Gandemer; Thierry Lamy; Mikael Roussel; Thierry Fest

doi:10.1080/10428194.2016.1225208

Detection of clonal heterogeneity and targetable mutations in myeloid sarcoma by high-throughput sequencing

Leuk Lymphoma. 2017 Apr;58(4):1008-1012. doi: 10.1080/10428194.2016.1225208. Epub 2016 Sep 23.

Authors

Cedric Pastoret^{1

2

3

4}, Roch Houot^{2

3

4

5}, Francisco Llamas-Gutierrez⁶, Marie-Laure Boulland¹, Tony Marchand^{2

3

4

5}, Patrick Tas⁶, Beatrice Ly-Sunnaram¹, Virginie Gandemer^{4

7

8}, Thierry Lamy^{2

3

4

5}, Mikael Roussel^{1

2

3

4}, Thierry Fest^{1

2

3

4}

Affiliations

¹ a Laboratoire d'Hématologie, Pole de Biologie, Centre Hospitalier Universitaire de Rennes , Rennes , France.
² b INSERM, UMRU917 , Rennes , France.
³ c Etablissement Français du Sang (EFS) de Bretagne , Rennes , France.
⁴ d Faculté de Medecine, Université de Rennes1 , Rennes , France.
⁵ e Service Hématologie Clinique, Centre Hospitalier Universitaire de Rennes , Rennes , France.
⁶ f Laboratoire d'Anatomopathologie, Pole de Biologie , Centre Hospitalier Universitaire de Rennes , Rennes , France.
⁷ g Service d'Oncologie-Hématologie Pédiatrique, Centre Hospitalier Universitaire de Rennes , Rennes , France.
⁸ h CNRS, UMR 6290 , Rennes , France.

PMID: 27659839
DOI: 10.1080/10428194.2016.1225208

No abstract available

Publication types

Letter

MeSH terms

Adolescent
Adult
Biomarkers, Tumor
Child
Child, Preschool
DNA Mutational Analysis
Female
Gene Expression Profiling
Genetic Heterogeneity*
High-Throughput Nucleotide Sequencing
Humans
Immunophenotyping
Infant
Infant, Newborn
Karyotyping
Male
Middle Aged
Mutation*
Prognosis
Sarcoma, Myeloid / diagnosis*
Sarcoma, Myeloid / genetics*
Sarcoma, Myeloid / mortality
Young Adult

Substances

Biomarkers, Tumor