Small artery mechanobiology: Roles of cellular and non-cellular elements

Microcirculation. 2016 Nov;23(8):611-613. doi: 10.1111/micc.12323.

Abstract

Small arteries and their component cellular and non-cellular elements are continually subjected to, and interact with, mechanical forces. Such interactions are key in both short- and long-term adaptation of the structure and function of the microcirculation to its local environment and metabolic requirements. Following this brief introduction is a series of papers presented as a symposium (Small Artery Mechanobiology: Roles of Cellular and Non-Cellular Elements) at the World Congress for Microcirculation, Kyoto 2015.

Keywords: artery; endothelium; extracellular matrix; mechanobiology; smooth muscle.

Publication types

  • Review

MeSH terms

  • Adaptation, Physiological*
  • Animals
  • Arteries / physiology*
  • Biomechanical Phenomena / physiology
  • Biophysics*
  • Humans
  • Mechanotransduction, Cellular / physiology
  • Microcirculation / physiology*