Centrosome movement in the early divisions of Caenorhabditis elegans: a cortical site determining centrosome position

J Cell Biol. 1989 Sep;109(3):1185-93. doi: 10.1083/jcb.109.3.1185.

Abstract

In Caenorhabditis elegans embryos, early blastomeres of the P cell lineage divide successively on the same axis. This axis is a consequence of the specific rotational movement of the pair of centrosomes and nucleus (Hyman, A. A., and J. G. White. 1987. J. Cell Biol. 105:2123-2135). A laser has been used to perturb the centrosome movements that determine the pattern of early embryonic divisions. The results support a previously proposed model in which a centrosome rotates towards its correct position by shortening of connections, possibly microtubules, between a centrosome and a defined site on the cortex of the embryo.

MeSH terms

  • Animals
  • Blastomeres / cytology*
  • Blastomeres / radiation effects
  • Blastomeres / ultrastructure
  • Caenorhabditis / embryology*
  • Cell Division / radiation effects
  • Embryo, Nonmammalian / cytology
  • Lasers
  • Microtubules / radiation effects
  • Microtubules / ultrastructure*
  • Mitosis / radiation effects