Parkinson's Disease and Cryptogenic Epilepsy

Case Rep Neurol Med. 2016:2016:3745631. doi: 10.1155/2016/3745631. Epub 2016 Sep 5.

Abstract

Epilepsy is an uncommon comorbidity of Parkinson's disease (PD) and has been considered not directly associated with PD. We present five patients (3 men and 2 women; ages 49-85) who had concomitant PD and cryptogenic epilepsy. Although rare, epilepsy can coexist with PD and their coexistence may influence the progression of PD. While this may be a chance association, an evolving understanding of the neurophysiological basis of either disease may suggest a mechanistic association.