Strategies to prevent TEVAR-related spinal cord ischemia

Vascular. 2017 Jun;25(3):307-315. doi: 10.1177/1708538116671235. Epub 2016 Sep 30.

Abstract

Spinal cord ischemia remains the Achilles' heel of thoracic and thoracoabdominal diseases management. Great improvements in morbidity and mortality have been obtained with the endovascular approach TEVAR (Thoracic Endovascular Aortic Repair) but this devastating complication continues to severely affect the quality of life, even if the primary success of the procedure - dissection/aneurysm exclusion - has been achieved. Several strategies to deal with this complication have been published in the literature over the time. Knowledge and technology have been evolving from identification of the risk factors associated with spinal cord ischemia, including lessons learned from open surgery, and from developments in the collateral network concept for spinal cord perfusion. In this comprehensive review, the authors cover several topics from the traditional measures comprising haemodynamic control, cerebrospinal drainage and neuroprotective drugs, to the staged-procedures approach, the emerging MISACE (minimally invasive selective segmental artery coil-embolization) and innovative neurologic monitoring such as NIRS (near-infrared spectroscopy) of the collateral network.

Keywords: TEVAR; cerebrospinal fluid drainage; spinal cord ischemia.

Publication types

  • Review

MeSH terms

  • Aorta, Thoracic / diagnostic imaging
  • Aorta, Thoracic / physiopathology
  • Aorta, Thoracic / surgery*
  • Aortic Diseases / diagnostic imaging
  • Aortic Diseases / physiopathology
  • Aortic Diseases / surgery*
  • Blood Vessel Prosthesis Implantation / adverse effects
  • Blood Vessel Prosthesis Implantation / methods*
  • Collateral Circulation
  • Endovascular Procedures / adverse effects
  • Endovascular Procedures / methods*
  • Hemodynamics
  • Humans
  • Regional Blood Flow
  • Risk Factors
  • Spinal Cord Ischemia / etiology
  • Spinal Cord Ischemia / physiopathology
  • Spinal Cord Ischemia / prevention & control*
  • Treatment Outcome