Novel genetic loci underlying human intracranial volume identified through genome-wide association

Affiliations

• ¹ Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.
• ² Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, the Netherlands.
• ³ Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of University of Southern California, Los Angeles, California, USA.
• ⁴ Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.
• ⁵ Lille University, Inserm, CHU Lille, Institut Pasteur de Lille, U1167 - RID-AGE - Risk factors and molecular determinants of aging-related diseases, Lille, France.
• ⁶ Framingham Heart Study, Framingham, Massachusetts, USA.
• ⁷ Department of Genetics and UNC Neuroscience Center, University of North Carolina (UNC), Chapel Hill, North Carolina, USA.
• ⁸ Department of Neurology, Department of Anesthesia/Critical Care Medicine, Department of Neurosurgery, Johns Hopkins University, Baltimore, Maryland, USA.
• ⁹ QIMR Berghofer Medical Research Institute, Brisbane, Australia.
• ¹⁰ Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.
• ¹¹ Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.
• ¹² Department of Psychiatry, Radboud University Medical Center, Nijmegen, the Netherlands.
• ¹³ Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, the Netherlands.
• ¹⁴ Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.
• ¹⁵ MRC-SGDP Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
• ¹⁶ Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miller School of Medicine, Miami, Florida, USA.
• ¹⁷ John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA.
• ¹⁸ German Center for Neurodegenerative Diseases (DZNE) Rostock/Greifswald, Greifswald, Germany.
• ¹⁹ Department of Psychiatry, University Medicine Greifswald, Greifswald, Germany.
• ²⁰ Brain Center Rudolf Magnus, Department of Psychiatry, UMC Utrecht, Utrecht, the Netherlands.
• ²¹ Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Canada.
• ²² The Royal College of Surgeons in Ireland, Dublin 2, Ireland.
• ²³ Department of Integrative Medical Biology and Umeå center for Functional Brain Imaging, Umeå University, Umeå, Sweden.
• ²⁴ Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, Illinois, USA.
• ²⁵ Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
• ²⁶ Department of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, Illinois, USA.
• ²⁷ Brain Research Imaging Centre, University of Edinburgh, Edinburgh, UK.
• ²⁸ Department of Computer Science, Lagos State University, Lagos, Nigeria.
• ²⁹ Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, Department of Neuroimaging Sciences, University of Edinburgh, Edinburgh, UK.
• ³⁰ Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, Australia.
• ³¹ Mathematics and Statistics, Murdoch University, Perth, Australia.
• ³² NORMENT - KG Jebsen Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
• ³³ NORMENT - KG Jebsen Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
• ³⁴ Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
• ³⁵ Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.
• ³⁶ Hospital for Sick Children, University of Toronto, Toronto, Canada.
• ³⁷ Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.
• ³⁸ Generation R Study Group, Erasmus Medical Center, Rotterdam, the Netherlands.
• ³⁹ Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands.
• ⁴⁰ Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, New York, New York, USA.
• ⁴¹ G.H. Sergievsky Center, Columbia University Medical Center, New York, New York, USA.
• ⁴² Department of Neurology, Columbia University Medical Center, New York, New York, USA.
• ⁴³ Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA.
• ⁴⁴ Cerebral Imaging Centre, Douglas Mental Health University Institute, Montreal, Canada.
• ⁴⁵ Department of Psychiatry and Biomedical Engineering, McGill University, Montreal, Canada.
• ⁴⁶ INSERM Unit U1219, University of Bordeaux, France.
• ⁴⁷ Lieber Institute for Brain Development, Baltimore, Maryland, USA.
• ⁴⁸ Interdepartmental Neuroscience Graduate Program, UCLA School of Medicine, Los Angeles, California, USA.
• ⁴⁹ Biological Psychology, Neuroscience Campus Amsterdam, Vrije Universiteit University and Vrije Universiteit Medical Center, Amsterdam, the Netherlands.
• ⁵⁰ Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, TU Dresden, Germany.
• ⁵¹ Department of Psychiatry, Massachusetts General Hospital, Boston, Masschusetts, USA.
• ⁵² Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, North Carolina, USA.
• ⁵³ NSERM Unit 1000 ″Neuroimaging and Psychiatry″, University Paris Sud, University Paris Descartes, Paris, France.
• ⁵⁴ Maison de Solenn, Adolescent Psychopathology and Medicine Department, APHP Hospital Cochin, Paris, France.
• ⁵⁵ Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.
• ⁵⁶ Harvard Medical School, Boston, Massachusetts, USA.
• ⁵⁷ Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Boston, Massachusetts, USA.
• ⁵⁸ NORMENT - KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Norway.
• ⁵⁹ Dr. Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.
• ⁶⁰ Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
• ⁶¹ Karakter Child and Adolescent Psychiatry University Center, Nijmegen, the Netherlands.
• ⁶² King's College London, Medical Research Council Social, Genetic and Developmental Psychiatry Centre, Institute of Psychology, Psychiatry and Neurosciene, London, UK.
• ⁶³ Central Institute of Mental Health, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany.
• ⁶⁴ Center of Biostatistics and Bioinformatics, University of Mississippi Medical Center, Jackson, Mississippi, USA.
• ⁶⁵ Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands.
• ⁶⁶ International Max Planck Research School for Language Sciences, Nijmegen, the Netherlands.
• ⁶⁷ Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Dresden, Germany.
• ⁶⁸ Department of Research and Development, Diakonhjemmet Hospital, Oslo, Norway.
• ⁶⁹ Department of Pharmacology, National University of Singapore, Singapore.
• ⁷⁰ Memory Aging and Cognition Centre (MACC), National University Health System, Singapore.
• ⁷¹ Department of Neurology, Clinical Division of Neurogeriatrics, Medical University Graz, Austria, Graz, Austria.
• ⁷² Institute of Medical Informatics, Statistics and Documentation, Medical University Graz, Austria, Graz, Austria.
• ⁷³ Max Planck Institute of Psychiatry, Department of Translational Research in Psychiatry, Munich, Germany.
• ⁷⁴ Department of Psychology, Yale University, New Haven, Connecticut, USA.
• ⁷⁵ UCL Institute of Neurology, London, United Kingdom and Epilepsy Society, Bucks, UK.
• ⁷⁶ Department of Medicine, Imperial College London, London, UK.
• ⁷⁷ Center for Neuroimaging, Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, USA.
• ⁷⁸ Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
• ⁷⁹ Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, Indiana, USA.
• ⁸⁰ Section for Experimental Psychopathology and Neuroimaging, Department of General Psychiatry, Heidelberg University, Heidelberg, Germany.
• ⁸¹ Lurie Center for Autism, Massachusetts General Hospital, Harvard Medical School, Lexington, Massachusetts, USA.
• ⁸² Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
• ⁸³ Centre for Cognitive Ageing and Cognitive Epidemiology, Psychology, University of Edinburgh, Edinburgh, UK.
• ⁸⁴ Donders Centre for Cognitive Neuroimaging, Radboud University, Nijmegen, The Netherlands.
• ⁸⁵ Reta Lila Weston Institute and Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK.
• ⁸⁶ Department of Biomedicine, Aarhus University, Aarhus, Denmark.
• ⁸⁷ The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus and Copenhagen, Denmark.
• ⁸⁸ Center for integrated Sequencing, iSEQ, Aarhus University, Aarhus, Denmark.
• ⁸⁹ UMR5296 University of Bordeaux, CNRS, CEA, Bordeaux, France.
• ⁹⁰ Department of Psychiatry, Yale University, New Haven, Connecticut, USA.
• ⁹¹ Olin Neuropsychiatric Research Center, Hartford, Connecticut, USA.
• ⁹² Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.
• ⁹³ Department of Psychiatry, EMGO Institute for Health and Care Research and Neuroscience Campus Amsterdam, VU University Medical Center/GGZ inGeest, Amsterdam, The Netherlands.
• ⁹⁴ Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health Intramural Research Program, National Institutes of Health, Bethesda, Maryland, USA.
• ⁹⁵ Center for Neurobehavioral Genetics, University of California, Los Angeles, California, USA.
• ⁹⁶ Department of Clinical Neuropsychology, VU University Amsterdam, Amsterdam, the Netherlands.
• ⁹⁷ Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh, UK.
• ⁹⁸ Division of Systems Neuroscience of Psychopathology, Translational Research Center, University Hospital of Psychiatry, University of Bern, Switzerland.
• ⁹⁹ School of Pedagogical and Educational Sciences, Erasmus University Rotterdam, Rotterdam, the Netherlands.
• ¹⁰⁰ Rush Institute for Healthy Aging, Rush University Medical Center, Chicago, Illinois, USA.
• ¹⁰¹ Department of Medical and Molecular Genetics, King's College London, London, UK.
• ¹⁰² The Jenner Institute Laboratories, University of Oxford, Oxford, UK.
• ¹⁰³ Department of Medicine and Psychiatry, University Hospital Marqués de Valdecilla, School of Medicine, University of Cantabria-IDIVAL, Santander, Spain.
• ¹⁰⁴ CIBERSAM (Centro Investigación Biomédica en Red Salud Mental), Santander, Spain.
• ¹⁰⁵ Psychosis Research Group, Department of Psychiatry and Trinity Translational Medicine Institute, Trinity College Dublin.
• ¹⁰⁶ Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
• ¹⁰⁷ Department of Neurology, University of Miami, Miller School of Medicine, Miami, Florida, USA.
• ¹⁰⁸ Department of Epidemiology and Public Health Sciences, University of Miami, Miller School of Medicine, Miami, Florida, USA.
• ¹⁰⁹ Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, VIC, Australia.
• ¹¹⁰ Centre for Youth Mental Health, The University of Melbourne, Melbourne, VIC, Australia.
• ¹¹¹ Department of Psychiatry, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.
• ¹¹² Multimodal Imaging Laboratory, Department of Neurosciences, University of California, San Diego, USA.
• ¹¹³ Department of Cognitive Sciences, University of California, San Diego, USA.
• ¹¹⁴ Icelandic Heart Association, Kopavogur, Iceland.
• ¹¹⁵ Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
• ¹¹⁶ Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
• ¹¹⁷ Queensland Brain Institute, University of Queensland, Brisbane, Australia.
• ¹¹⁸ Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
• ¹¹⁹ School of Computing Engineering and Mathematics, Western Sydney University, Parramatta, Australia.
• ¹²⁰ Neuroimaging Unit,Technological Facilities. Valdecilla Biomedical Research Institute IDIVAL, Santander, Cantabria, Spain.
• ¹²¹ Institut Pasteur, Paris, France.
• ¹²² Department of Genetics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
• ¹²³ GeneSTAR Research Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
• ¹²⁴ Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.
• ¹²⁵ Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
• ¹²⁶ Brain Center Rudolf Magnus, Human Neurogenetics Unit, UMC Utrecht, Utrecht, the Netherlands.
• ¹²⁷ Department of Psychiatry and Human Behavior, University of California-Irvine, Irvine, California, USA.
• ¹²⁸ NORMENT - KG Jebsen Centre, Department of Psychology, University of Oslo, Oslo, Norway.
• ¹²⁹ Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA.
• ¹³⁰ FMRIB Centre, University of Oxford, Oxford, UK.
• ¹³¹ University of Wuerzburg, Department of Psychiatry, Psychosomatics and Psychotherapy, Wuerzburg, Germany.
• ¹³² Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.
• ¹³³ Biospective Inc, Montreal, Quebec, Canada, Montréal, Québec, Canada.
• ¹³⁴ Department of Clinical Neuroscience, Centre for Psychiatric Research, Karolinska Institutet, Stockholm, Sweden.
• ¹³⁵ South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine Brownsville/Edinburg/San Antonio, Texas, USA.
• ¹³⁶ Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
• ¹³⁷ Department of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
• ¹³⁸ National Ageing Research Institute, Royal Melbourne Hospital, Melbourne, Australia.
• ¹³⁹ Academic Unit for Psychiatry of Old Age, University of Melbourne, Melbourne, Australia.
• ¹⁴⁰ Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.
• ¹⁴¹ Departments of Psychiatry, Neurology, and Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
• ¹⁴² Dementia Collaborative Research Centre - Assessment and Better Care, UNSW, Sydney, Australia.
• ¹⁴³ Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, the Netherlands.
• ¹⁴⁴ Department of Psychology, Center for Brain Science, Harvard University, Cambridge, Massachusetts, USA.
• ¹⁴⁵ Department of Evolution and Genetics, Dagestan State University, Makhachkala, Dagestan, Russia.
• ¹⁴⁶ The Mind Research Network and LBERI, Albuquerque, New Mexico, USA.
• ¹⁴⁷ Department of ECE, University of New Mexico, Albuquerque, New Mexico, USA.
• ¹⁴⁸ Centre for Neuroimaging and Cognitive Genomics (NICOG), Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine Nursing and Health Sciences, National University of Ireland Galway, Galway, Ireland.
• ¹⁴⁹ Academic Medicine Research Institute, Duke-NUS Graduate Medical School, Singapore.
• ¹⁵⁰ Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
• ¹⁵¹ Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel, Switzerland.
• ¹⁵² Institute of Human Genetics, University of Bonn, Bonn, Germany.
• ¹⁵³ Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany.
• ¹⁵⁴ Center for Multimodal Imaging and Genetics, University of California, San Diego, California, USA.
• ¹⁵⁵ Department of Neurosciences, University of California, San Diego, California, USA.
• ¹⁵⁶ Department of Radiology, University of California, San Diego, California, USA.
• ¹⁵⁷ Department of Psychiatry, University of California, San Diego, California, USA.
• ¹⁵⁸ Department of Cognitive Science, University of California, San Diego, California, USA.
• ¹⁵⁹ Avera Institute for Human Genetics, Sioux Falls, South Dakota, USA.
• ¹⁶⁰ Program in Translational NeuroPsychiatric Genomics, Departments of Neurology and Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts, USA.
• ¹⁶¹ Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.
• ¹⁶² Broad Institute, Cambridge, Massachusetts, USA.
• ¹⁶³ Faculty of Health and Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, Australia.
• ¹⁶⁴ Neurology Division, Beaumont Hospital, Dublin, 9, Ireland.
• ¹⁶⁵ Department of Neurology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, Belgium.
• ¹⁶⁶ Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.
• ¹⁶⁷ Cognitive Genetics and Cognitive Therapy Group, Neuroimaging, Cognition and Genomics Centre (NICOG) and NCBES Galway Neuroscience Centre, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland.
• ¹⁶⁸ Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity College Institute of Psychiatry, Trinity College Dublin, Dublin 8, Ireland.
• ¹⁶⁹ Janssen Research and Development, LLC, Titusville, New Jersey, USA.
• ¹⁷⁰ Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, CCM, Berlin, Germany.
• ¹⁷¹ Intramural Research Program of the National Institute on Aging, Baltimore, Maryland, USA.
• ¹⁷² Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, USA.
• ¹⁷³ Robertson Center for Biostatistics, University of Glasgow, Glasgow, UK.
• ¹⁷⁴ Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, USA.
• ¹⁷⁵ University of Texas Health Science Center, San Antonio, Texas, USA.
• ¹⁷⁶ Division of Cerebral Integration, National Institute for Physiological Sciences, Aichi, Japan.
• ¹⁷⁷ Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
• ¹⁷⁸ Department of Psychiatry, Osaka University Graduate School of Medicine, Osaka, Japan.
• ¹⁷⁹ Molecular Research Center for Children's Mental Development, United Graduate School of Child Development, Osaka University, Osaka, Japan.
• ¹⁸⁰ Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany.
• ¹⁸¹ German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany.
• ¹⁸² Department of Psychology, VU University Amsterdam, Amsterdam, the Netherlands.
• ¹⁸³ Department of Psychiatry, University of Iowa, Iowa City, Iowa, USA.
• ¹⁸⁴ HMNC Brain Health, Munich, Germany.
• ¹⁸⁵ Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany.
• ¹⁸⁶ Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Japan.
• ¹⁸⁷ Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
• ¹⁸⁸ NICHD Brain and Tissue Bank for Developmental Disorders, University of Maryland Medical School, Baltimore, Maryland, USA.
• ¹⁸⁹ School of Psychology, University of Sussex, Brighton, UK.
• ¹⁹⁰ Institute of Cognitive Neuroscience, University College London, London, UK.
• ¹⁹¹ Department of Neuroinformatics, Araya Brain Imaging, Tokyo, Japan.
• ¹⁹² Medical University of Lodz, Lodz, Poland.
• ¹⁹³ Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.
• ¹⁹⁴ Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, Maryland, USA.
• ¹⁹⁵ Neuroscience Research Australia, Sydney, Australia.
• ¹⁹⁶ School of Medical Sciences, UNSW, Sydney, Australia.
• ¹⁹⁷ Columbia University Medical Center, New York, New York, USA.
• ¹⁹⁸ Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.
• ¹⁹⁹ Department of Neurology, University of Washington, Seattle, Washington, USA.
• ²⁰⁰ Department of Epidemiology, University of Washington, Seattle, Washington, USA.
• ²⁰¹ Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
• ²⁰² Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
• ²⁰³ Department of Psychiatry, University of Oxford, Oxford, UK.
• ²⁰⁴ NIHR Dementia Biomedical Research Unit, King's College London, London, UK.
• ²⁰⁵ Imaging of Dementia and Aging (IDeA) Laboratory, Department of Neurology and Center for Neuroscience, University of California at Davis, Sacramento, California, USA.
• ²⁰⁶ Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
• ²⁰⁷ Centre for Advanced Imaging, University of Queensland, Brisbane, Australia.
• ²⁰⁸ Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy.
• ²⁰⁹ Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
• ²¹⁰ University of Liverpool, Institute of Translational Medicine, Liverpool, UK.
• ²¹¹ Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
• ²¹² German Center for Cardiovascular Research (DZHK e.V.), partner site Greifswald, Germany.
• ²¹³ Department of Statistics and Warwick Manufacturing Group, University of Warwick, Coventry, UK.
• ²¹⁴ Department of Medical Informatics Erasmus MC, Rotterdam, the Netherlands.
• ²¹⁵ Faculty of Applied Sciences, Delft University of Technology, Delft, the Netherlands.
• ²¹⁶ Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.
• ²¹⁷ Rotman Research Institute, University of Toronto, Toronto, Canada.
• ²¹⁸ Departments of Psychology and Psychiatry, University of Toronto, Canada.
• ²¹⁹ Child Mind Institute, New York, New York, USA.
• ²²⁰ Department of Physiology, University of Toronto, Toronto, Canada.
• ²²¹ Department of Nutritional Sciences, University of Toronto, Toronto, Canada.
• ²²² Department of Radiology, University of Calgary, Calgary, Canada.
• ²²³ Department of Clinical Neuroscience, University of Calgary, Calgary, Canada.
• ²²⁴ Department of Medicine, University of Washington, Seattle, Washington, USA.
• ²²⁵ Department of Health Services, University of Washington, Seattle, Washington, USA.
• ²²⁶ Group Health Research Institute, Group Health, Seattle, Washington, USA.
• ²²⁷ Department of Developmental Disability Neuropsychiatry, School of Psychiatry, UNSW Medicine, Australia.
• ²²⁸ Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Pediatrics at Harbor-UCLA Medical Center, Torrance, California, USA.
• ²²⁹ Evelyn F. McKnight Brain Institute, University of Miami, Miller School of Medicine, Miami, Florida, USA.
• ²³⁰ Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, Australia.
• ²³¹ Department of Neuroimaging, Institute of Psychiatry, King's College London, London, UK.
• ²³² Biomedical Research Centre for Mental Health, King's College London, London, UK.
• ²³³ Biomedical Research Unit for Dementia, King's College London, London, UK.
• ²³⁴ MRC Edinburgh Brain Bank, University of Edinburgh, Academic Department of Neuropathology, Centre for Clinical Brain Sciences, Edinburgh, UK.
• ²³⁵ Institute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, Finland.
• ²³⁶ Neurocentre Neurology, Kuopio University Hospital, Finland.
• ²³⁷ Department of Medicine, Peninsula Health and Monash University, Melbourne, Australia.
• ²³⁸ Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK.
• ²³⁹ Laboratory of Neuro Imaging, Institute for Neuroimaging and Informatics, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.
• ²⁴⁰ Brain Resource Center, Johns Hopkins University, Baltimore, Maryland, USA.
• ²⁴¹ Georgia State University, Atlanta, Georgia, USA.
• ²⁴² Institute for Neurodegenerative Disorders, UMR 5293, CEA, CNRS, Université de Bordeaux, France.
• ²⁴³ Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands.
• ²⁴⁴ Genentech Inc., South San Francisco, California, USA.
• ²⁴⁵ Department of Psychiatry and Leiden Institute for Brain and Cognition, Leiden University Medical Center, Leiden, The Netherlands.
• ²⁴⁶ Neuroimaging Centre, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
• ²⁴⁷ Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
• ²⁴⁸ Departments of Psychiatry, Neurology, Neuroscience and the Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
• ²⁴⁹ Center for Imaging of Neurodegenerative Disease, San Francisco VA Medical Center, University of California, San Francisco, California, USA.
• ²⁵⁰ Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
• ²⁵¹ Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.
• ²⁵² Institute of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria.
• ²⁵³ Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.
• ²⁵⁴ Intramural Research Program, NIA, NIH, Bethesda, Maryland, USA.
• ²⁵⁵ Institute of Molecular Medicine and Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA.
• ²⁵⁶ Department of Neurology, Bordeaux University Hospital, Bordeaux, France.
• ²⁵⁷ Department of Neurology, Erasmus MC, Rotterdam, the Netherlands.