Abstract
Measuring substrate and/or product concentration can create a major bottleneck for synthetic and biosynthetic processes. Here we report the development and substrate screening of a whole cell biosensor to detect biomass-derived aromatic chemical building blocks, supporting the use of sustainable feedstocks in the bulk and fine chemical industries.
MeSH terms
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Aldehyde Oxidoreductases / genetics
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Aldehyde Oxidoreductases / metabolism
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Benzene Derivatives / analysis*
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Benzene Derivatives / metabolism
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Biomass*
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Biosensing Techniques / methods*
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Coumaric Acids / analysis
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Coumaric Acids / metabolism
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Escherichia coli / metabolism
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Genetic Vectors / genetics
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Genetic Vectors / metabolism
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Promoter Regions, Genetic
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Substrate Specificity
Substances
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Benzene Derivatives
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Coumaric Acids
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ferulic acid
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Aldehyde Oxidoreductases