ASXL1 mutations are frequent in de novo AML with trisomy 8 and confer an unfavorable prognosis

Xiangping Zong; Hong Yao; Lijun Wen; Liang Ma; Qinrong Wang; Zhiluo Yang; Tongtong Zhang; Suning Chen; Wu Depei

doi:10.1080/10428194.2016.1179296

ASXL1 mutations are frequent in de novo AML with trisomy 8 and confer an unfavorable prognosis

Leuk Lymphoma. 2017 Jan;58(1):204-206. doi: 10.1080/10428194.2016.1179296. Epub 2016 Oct 13.

Authors

Xiangping Zong^{1

2}, Hong Yao^{1

2}, Lijun Wen^{1

2}, Liang Ma^{1

2}, Qinrong Wang^{1

2}, Zhiluo Yang^{1

2}, Tongtong Zhang^{1

2}, Suning Chen^{1

2}, Wu Depei^{1

2}

Affiliations

¹ a Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health , The First Affiliated Hospital of Soochow University , Suzhou , PR China.
² b Collaborative Innovation Center of Hematology , Soochow University , Suzhou , PR China.

PMID: 27736271
DOI: 10.1080/10428194.2016.1179296

No abstract available

Publication types

Letter

MeSH terms

Acute Disease
Adolescent
Adult
Aged
Aged, 80 and over
Child
Chromosomes, Human, Pair 8 / genetics
Female
Humans
Kaplan-Meier Estimate
Leukemia, Myeloid / genetics*
Leukemia, Myeloid / pathology
Male
Middle Aged
Mutation*
Prognosis
Repressor Proteins / genetics*
Trisomy / genetics*
Young Adult

Substances

ASXL1 protein, human
Repressor Proteins

Supplementary concepts

Chromosome 8, trisomy