Hypertrophic Cardiomyopathy: Cell-to-Cell Imbalance in Gene Expression and Contraction Force as Trigger for Disease Phenotype Development

Circ Res. 2016 Oct 14;119(9):992-995. doi: 10.1161/CIRCRESAHA.116.309804.

Authors

Theresia Kraft¹, Judith Montag², Ante Radocaj², Bernhard Brenner²

Affiliations

¹ From the Institute of Molecular and Cell Physiology, Hannover Medical School, Germany. [email protected].
² From the Institute of Molecular and Cell Physiology, Hannover Medical School, Germany.

PMID: 27737944
DOI: 10.1161/CIRCRESAHA.116.309804

No abstract available

Keywords: allelic imbalance; cardiomyocytes; cardiomyopathy; contractile protein; heart failure; hypertrophic; myosin heavy chains.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Cardiomyopathy, Hypertrophic / genetics*
Cardiomyopathy, Hypertrophic / physiopathology*
Cell Communication / physiology*
Gene Expression
Humans
Mutation / physiology
Myocardial Contraction / physiology*
Phenotype*