1 Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada;; Keenan Research Centre and Li Ka Shing Knowledge Institute, Department of Critical Care, St Michael's Hospital, Toronto, Canada.
2 Keenan Research Centre and Li Ka Shing Knowledge Institute, Department of Critical Care, St Michael's Hospital, Toronto, Canada;; Department of Critical Care Medicine, Peking University Third Hospital, Beijing 100191, China.