Multiple giant cell tumors of bone arising from multiple fatty tumors

Alireza Eajazi; Arvin Kheterpal; Susan Kattapuram; Gunnlaugur Petur Nielsen; Daniel Ira Rosenthal

doi:10.1007/s00256-016-2498-0

Multiple giant cell tumors of bone arising from multiple fatty tumors

Skeletal Radiol. 2017 Jan;46(1):117-121. doi: 10.1007/s00256-016-2498-0. Epub 2016 Oct 22.

Authors

Alireza Eajazi¹, Arvin Kheterpal², Susan Kattapuram¹, Gunnlaugur Petur Nielsen³, Daniel Ira Rosenthal¹

Affiliations

¹ Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Yawkey 6E, 55 Fruit Street, Boston, MA, 02114, USA.
² Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Yawkey 6E, 55 Fruit Street, Boston, MA, 02114, USA. [email protected].
³ Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Warren 2, 55 Fruit Street, Boston, MA, USA.

PMID: 27771752
DOI: 10.1007/s00256-016-2498-0

Abstract

We describe a patient with a history of giant cell tumor who over the course of 18 years developed multiple fat containing osseous lesions in the pelvis and spine. Two of these lesions subsequently evolved into biopsy proven giant cell tumor of bone. To our knowledge, this phenomenon of giant cell tumors evolving from fat containing lesions has not been described.

Keywords: Bone; Fatty tumor; Giant cell tumor (GCT); Multifocal; Recurrent.

Publication types

Case Reports

MeSH terms

Adult
Biopsy
Bone Neoplasms / diagnostic imaging*
Bone Neoplasms / pathology*
Bone Neoplasms / therapy
Giant Cell Tumor of Bone / diagnostic imaging*
Giant Cell Tumor of Bone / pathology*
Giant Cell Tumor of Bone / therapy
Humans
Lipomatosis / pathology*
Male
Pelvic Neoplasms / diagnostic imaging*
Pelvic Neoplasms / pathology*
Pelvic Neoplasms / therapy
Spinal Neoplasms / diagnostic imaging*
Spinal Neoplasms / pathology*
Spinal Neoplasms / therapy