Successful management of Mycobacterium haemophilum lower extremity cutaneous infection in a matched-unrelated donor stem cell transplant recipient

Aliyah Baluch; Yanina Pasikhova; Matthew Snyder

doi:10.1111/tid.12627

Successful management of Mycobacterium haemophilum lower extremity cutaneous infection in a matched-unrelated donor stem cell transplant recipient

Transpl Infect Dis. 2017 Feb;19(1). doi: 10.1111/tid.12627. Epub 2016 Dec 16.

Authors

Aliyah Baluch¹, Yanina Pasikhova², Matthew Snyder³

Affiliations

¹ Division of Infectious Diseases, Department of Internal Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
² Division of Infectious Diseases, Department of Pharmacy, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
³ Department of Pharmacy, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

PMID: 27775824
DOI: 10.1111/tid.12627

Abstract

Nontuberculous mycobacterial infections can often occur in individuals with adequate immune function. Such infections typically have cutaneous involvement and are caused by rapidly growing mycobacterium. Other nontuberculous mycobacteria species, like Mycobacterium haemophilum, almost always present as opportunistic infections occurring in severely immunocompromised hosts. Here, we present a complicated and protracted course of diagnosing M. haemophilum lower extremity cutaneous infection in a matched-unrelated donor stem cell transplant recipient.

Keywords: Mycobacterium haemophilum; nontuberculous mycobacteria; nontuberculous mycobacterial infection; opportunistic infection; stem cell transplantation.

Publication types

Case Reports

MeSH terms

Anti-Bacterial Agents / therapeutic use*
Biopsy
Cellulitis / complications
Cellulitis / diagnosis
Cellulitis / drug therapy*
Cellulitis / microbiology
Ciprofloxacin / therapeutic use
Clarithromycin / therapeutic use
Female
Graft vs Host Disease / diagnosis
Graft vs Host Disease / drug therapy
Hematopoietic Stem Cell Transplantation / adverse effects*
Humans
Immunocompromised Host
Immunosuppression Therapy / adverse effects
Immunosuppressive Agents / adverse effects
Immunosuppressive Agents / therapeutic use
Leukemia, Myeloid, Acute / surgery*
Lower Extremity
Middle Aged
Mycobacterium Infections, Nontuberculous / complications
Mycobacterium Infections, Nontuberculous / diagnosis
Mycobacterium Infections, Nontuberculous / drug therapy*
Mycobacterium Infections, Nontuberculous / microbiology
Mycobacterium haemophilum / isolation & purification*
Opportunistic Infections / complications
Opportunistic Infections / diagnosis
Opportunistic Infections / drug therapy*
Opportunistic Infections / microbiology
Rifabutin / therapeutic use
Tacrolimus / adverse effects
Tacrolimus / therapeutic use
Unrelated Donors

Substances

Anti-Bacterial Agents
Immunosuppressive Agents
Rifabutin
Ciprofloxacin
Clarithromycin
Tacrolimus