Subchondral insufficiency fracture of the knee: A recognizable associated soft tissue edema pattern and a similar distribution among men and women

Eur J Radiol. 2016 Nov;85(11):2096-2103. doi: 10.1016/j.ejrad.2016.08.016. Epub 2016 Aug 26.

Abstract

Objective: Primary: to describe the presence and pattern of soft tissue edema in subchondral insufficiency fractures of the knee (SIFK). Secondary: to investigate the gender distribution and identify factors associated with disease progression.

Methods: MR images of 74 SIFKs in 74 patients were retrospectively reviewed for soft tissue edema presence and location, meniscal tears and extrusion and synovitis. The clinical records were reviewed for age, gender, and BMI. Follow up examinations were reviewed to assess for progression. Data were analyzed for gender distribution and for association between each imaging finding as a predictor of SIFK location and progression.

Results: Soft tissue edema was present in 89% (66/74) of SIFK. It was located around the MCL in 78% (58/74), posterior to and abutting on the posterior distal femur in 68% (50/74), around to the tibia in only 18% (13/74), but when present it strongly predicted the presence of a medial tibial plateau SIFK (p=5.6×10^-12). Edema extended to the vastus medialis fascia in 51% (38/74) and vastus lateralis fascia in 24% (18/74). Gender distribution was 1:1 (males=38, females=36), most common in the 6th decade (29/74, 39%). Lesion progression showed a trend towards being more common in females (8/9, 89%) compared to males (9/16, 56%), and in patients with meniscal extrusion (≥3mm) (13/14, 93%) compared to those with no extrusion (2/7, 29%).

Conclusion: A recognizable soft tissue edema pattern is seen in SIFK and may have an important role in early diagnosis. Also, SIFK may affect equally males and females in the 6th decade and may progress more in females. Meniscal extrusion may predispose to disease progression.

Keywords: Insufficiency fracture; Knee; Meniscus; Osteoarthritis; Spontaneous osteonecrosis of the knee.

MeSH terms

  • Adult
  • Aged
  • Connective Tissue / pathology*
  • Disease Progression
  • Edema / pathology*
  • Female
  • Follow-Up Studies
  • Fractures, Stress / diagnostic imaging*
  • Fractures, Stress / epidemiology
  • Fractures, Stress / pathology
  • Humans
  • Incidence
  • Knee Injuries / diagnostic imaging*
  • Knee Injuries / epidemiology
  • Knee Injuries / pathology
  • Knee Joint / pathology*
  • Magnetic Resonance Imaging* / methods
  • Male
  • Menisci, Tibial / diagnostic imaging*
  • Menisci, Tibial / pathology
  • Middle Aged
  • Retrospective Studies
  • Sex Factors
  • Tibial Meniscus Injuries / diagnostic imaging*
  • Tibial Meniscus Injuries / pathology
  • United States / epidemiology
  • Young Adult