Cardiac troponin I concentrations, electrocardiographic and echocardiographic variables remained unchanged in dogs experimentally infected with Ehrlichia canis

Lamprini Kalogianni; Christos K Koutinas; Konstantina Theodorou; Panagiotis G Xenoulis; Jan S Suchodolski; Shimon Harrus; Joerg M Steiner; Victoria I Siarkou; Mathios E Mylonakis

doi:10.1016/j.tvjl.2016.09.007

Cardiac troponin I concentrations, electrocardiographic and echocardiographic variables remained unchanged in dogs experimentally infected with Ehrlichia canis

Vet J. 2016 Nov:217:109-111. doi: 10.1016/j.tvjl.2016.09.007. Epub 2016 Sep 28.

Authors

Lamprini Kalogianni¹, Christos K Koutinas², Konstantina Theodorou¹, Panagiotis G Xenoulis³, Jan S Suchodolski³, Shimon Harrus⁴, Joerg M Steiner³, Victoria I Siarkou⁵, Mathios E Mylonakis¹

Affiliations

¹ Companion Animal Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki (SVM-AUTh), 11 Stavrou Voutyra Street, 54627, Thessaloniki, Greece.
² Companion Animal Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki (SVM-AUTh), 11 Stavrou Voutyra Street, 54627, Thessaloniki, Greece. Electronic address: [email protected].
³ Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, 4474 TAMU, College Station, TX 77843, USA.
⁴ Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, P.O. Box 12, Rehovot 76100, Israel.
⁵ Laboratory of Microbiology and Infectious Diseases, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, University Campus, 54124, Thessaloniki, Greece.

PMID: 27810200
DOI: 10.1016/j.tvjl.2016.09.007

Abstract

Canine monocytic ehrlichiosis (CME, Ehrlichia canis) has occasionally been associated with myocardial injury. The aim of the present study was to serially measure and evaluate cardiac troponin I (cTnI) concentrations in dogs with experimentally induced acute and subclinical CME and to evaluate potential associations between cTnI concentration and an array of echocardiographic and electrocardiographic parameters. Serum cTnI concentration and simultaneous echocardiographic and electrocardiographic recordings were evaluated in 12 healthy Beagle dogs prior to experimental infection and on days 20 and 90 post-inoculation with E. canis. Almost all serum cTnI concentrations were below the limit of detection and selected electrocardiographic and echocardiographic parameters remained unchanged throughout the study.

Keywords: Dog; Echocardiography; Monocytic ehrlichiosis; Myocarditis; Troponin I.

MeSH terms

Acute Disease
Animals
Asymptomatic Infections
Dog Diseases / diagnostic imaging*
Dog Diseases / microbiology
Dogs
Echocardiography / veterinary
Ehrlichia canis / physiology*
Ehrlichiosis / diagnostic imaging
Ehrlichiosis / microbiology
Ehrlichiosis / veterinary*
Electrocardiography / veterinary
Female
Male
Monocytes / microbiology
Troponin I / blood*

Substances

Troponin I