From Protein-RNA Predictions toward a Peptide-RNA Code

Kristopher W Brannan; Gene W Yeo

doi:10.1016/j.molcel.2016.10.023

From Protein-RNA Predictions toward a Peptide-RNA Code

Mol Cell. 2016 Nov 3;64(3):437-438. doi: 10.1016/j.molcel.2016.10.023.

Authors

Kristopher W Brannan¹, Gene W Yeo²

Affiliations

¹ Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
² Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Stem Cell Program and Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Molecular Engineering Laboratory, A(∗)STAR, Singapore. Electronic address: [email protected].

PMID: 27814488
DOI: 10.1016/j.molcel.2016.10.023

Abstract

The RNA field is undergoing a renaissance, with a deluge of proteins being identified to bind RNA. Two reports now introduce proteome-wide approaches that identify the peptides that are crosslinked to RNA (Castello et al., 2016; He et al., 2016).

Publication types

Comment

MeSH terms

Animals
Binding Sites
Chromatin / chemistry*
Chromatin / metabolism
Chromatin / radiation effects
Gene Expression
Humans
Mice
Mouse Embryonic Stem Cells / cytology
Mouse Embryonic Stem Cells / metabolism*
Mouse Embryonic Stem Cells / radiation effects
Nuclear Proteins / chemistry*
Nuclear Proteins / genetics
Nuclear Proteins / metabolism
Nucleic Acid Conformation
Peptide Mapping / methods
Photochemical Processes
Protein Binding
Protein Domains
Proteome / chemistry*
Proteome / genetics
Proteome / metabolism
RNA, Untranslated / chemistry*
RNA, Untranslated / genetics
RNA, Untranslated / metabolism
RNA-Binding Proteins / chemistry*
RNA-Binding Proteins / genetics
RNA-Binding Proteins / metabolism
Ultraviolet Rays

Substances

Chromatin
Nuclear Proteins
Proteome
RNA, Untranslated
RNA-Binding Proteins