Systemic inflammatory markers and sources of social support among older adults in the Memory Research Unit cohort

J Health Psychol. 2019 Mar;24(3):397-406. doi: 10.1177/1359105316676331. Epub 2016 Nov 4.

Abstract

Potential associations between systemic inflammation and social support received by a sample of 120 older adults were examined here. Inflammatory markers, cognitive function, social support and psychosocial wellbeing were evaluated. A structural equation modelling approach was used to analyse the data. The model was a good fit χ1082=256.13 , p < 0.001; comparative fit index = 0.973; Tucker-Lewis Index = 0.962; root mean square error of approximation = 0.021; standardised root mean-square residual = 0.074). Chemokine levels were associated with increased age ( β = 0.276), receipt of less social support from friends ( β = -0.256) and body mass index ( β = -0.256). Results are discussed in relation to social signal transduction theory.

Keywords: age; health psychology; protective factors; quantitative methods.

Publication types

  • Observational Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aging / immunology*
  • Body Mass Index*
  • Chemokines / blood*
  • Cohort Studies
  • Female
  • Humans
  • Inflammation / blood*
  • Inflammation / epidemiology
  • Male
  • Middle Aged
  • Personal Satisfaction*
  • Protective Factors
  • Social Support*

Substances

  • Chemokines