Exercise-induced bronchoconstriction in athletes - A qualitative assessment of symptom perception

Respir Med. 2016 Nov:120:36-43. doi: 10.1016/j.rmed.2016.09.017. Epub 2016 Sep 25.

Abstract

Background: A poor relationship between perceived respiratory symptoms and objective evidence of exercise-induced bronchoconstriction (EIB) in athletes is often reported; however, the reasons for this disconnect remain unclear. The primary aim of this study was to utilise a qualitative-analytical approach to compare respiratory symptoms in athletes with and without objectively confirmed EIB.

Methods: Endurance athletes who had previously undergone bronchoprovocation test screening for EIB were divided into sub-groups, based on the presence or absence of EIB ± heightened self-report of dyspnoea: (i) EIB-Dys- (ii) EIB + Dys+ (iii) EIB + Dys- (iv) EIB-Dys+. All athletes underwent a detailed semi-structured interview.

Results: Twenty athletes completed the study with an equal distribution in each sub-group (n = 5). Thematic analysis of individual narratives resulted in four over-arching themes: 1) Factors aggravating dyspnoea, 2) Exercise limitation, 3) Strategies to control dyspnoea, 4) Diagnostic accuracy. The anatomical location of symptoms varied between EIB + Dys + athletes and EIB-Dys + athletes. All EIB-Dys + reported significantly longer recovery times following high-intensity exercise in comparison to all other sub-groups. Finally, EIB + Dys + reported symptom improvement following beta-2 agonist therapy, whereas EIB-Dys + deemed treatment ineffective.

Conclusion: A detailed qualitative approach to the assessment of breathlessness reveals few features that distinguish between EIB and non-EIB causes of exertional dyspnoea in athletes. Important differences that may provide value in clinical work-up include (i) location of symptoms, (ii) recovery time following exercise and (iii) response to beta-2 agonist therapy. Overall these findings may inform clinical evaluation and development of future questionnaires to aid clinic-based assessment of athletes with dyspnoea.

Keywords: Athletes; Dyspnoea; Exercise-induced bronchoconstriction; Perception; Qualitative methods; Respiratory symptoms.

Publication types

  • Comparative Study

MeSH terms

  • Adrenergic beta-2 Receptor Agonists / therapeutic use
  • Adult
  • Asthma, Exercise-Induced / diagnosis*
  • Asthma, Exercise-Induced / physiopathology
  • Asthma, Exercise-Induced / psychology
  • Athletes
  • Bronchoconstriction / drug effects
  • Bronchoconstriction / physiology*
  • Diagnostic Self Evaluation
  • Dyspnea / diagnosis*
  • Dyspnea / drug therapy
  • Dyspnea / psychology
  • Evaluation Studies as Topic*
  • Exercise / physiology
  • Female
  • Forced Expiratory Volume
  • Humans
  • Male
  • Middle Aged
  • Perception*
  • Respiratory Function Tests / methods
  • Self Report
  • Surveys and Questionnaires
  • Vital Capacity

Substances

  • Adrenergic beta-2 Receptor Agonists