Biochemical Hyperthyroidism in a Newborn Baby Caused by Assay Interaction from Biotin Intake

Eur Thyroid J. 2016 Sep;5(3):212-215. doi: 10.1159/000448034. Epub 2016 Aug 12.

Abstract

We describe a case of biochemical neonatal thyrotoxicosis caused by biotin supplementation. Biotin may interact with thyroid function testing to imitate thyrotoxicosis with low thyroid-stimulating hormone and elevated triiodothyronine and thyroxine levels.

Keywords: Assay interaction; Biotin; Neonatal hyperthyroidism.