Mother-To-Child Transmission of KPC Carbapenemase-Producing Klebsiella Pneumoniae at Birth

Pediatr Infect Dis J. 2017 Feb;36(2):228-229. doi: 10.1097/INF.0000000000001403.

Abstract

We report on a mother-to-child transmission of KPC carbapenemase-producing Klebsiella pneumoniae at birth followed by subsequent cases in the neonatal intensive care unit. Molecular analysis of isolates showed production of KPC-3 enzyme. The only potential risk factor identified for the mother was previous activity as a caregiver. Present findings suggest consideration of proactive surveillance in pregnant women with risk factors for colonization.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Bacterial Proteins*
  • Carbapenems
  • Female
  • Humans
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical*
  • Klebsiella Infections* / microbiology
  • Klebsiella Infections* / transmission
  • Klebsiella pneumoniae* / drug effects
  • Klebsiella pneumoniae* / enzymology
  • Klebsiella pneumoniae* / isolation & purification
  • Microbial Sensitivity Tests
  • Pregnancy
  • beta-Lactam Resistance
  • beta-Lactamases*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Carbapenems
  • beta-Lactamases
  • carbapenemase