Definitive Chemoradiotherapy for Advanced Pulmonary Sarcomatoid Carcinoma

Intern Med. 2016;55(22):3325-3330. doi: 10.2169/internalmedicine.55.6990. Epub 2016 Nov 15.

Abstract

Pulmonary sarcomatoid carcinoma is a rare subtype of non-small cell lung cancer with a poor prognosis. We herein report on a case of pulmonary sarcomatoid carcinoma that was treated successfully by concurrent chemoradiotherapy. A 65-year-old man was diagnosed to have pulmonary pleomorphic carcinoma (clinical T4N2M0 stage IIIB). He received concurrent chemoradiotherapy (60 Gy of radiotherapy in 30 fractionations and two courses of chemotherapy with carboplatin and paclitaxel). After chemoradiotherapy, a significant reduction of the tumor size was observed. Two courses of adjuvant chemotherapy were performed. He is currently alive at 15 months after the first treatment without any recurrence or metastasis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antineoplastic Agents / therapeutic use*
  • Carboplatin / therapeutic use*
  • Carcinoma, Non-Small-Cell Lung / therapy*
  • Chemoradiotherapy*
  • Chemotherapy, Adjuvant
  • Humans
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / therapy*
  • Male
  • Neoplasm Staging
  • Paclitaxel / therapeutic use*
  • Tomography, X-Ray Computed

Substances

  • Antineoplastic Agents
  • Carboplatin
  • Paclitaxel