Parent reported sleep problems in preschool children with sickle cell anemia and controls in East London

Pediatr Blood Cancer. 2017 Jun;64(6). doi: 10.1002/pbc.26337. Epub 2016 Nov 15.

Abstract

Snoring and poor sleep may affect cognition, particularly in young children with chronic conditions. Parents of London preschoolers with sickle cell anemia (SCA; n = 22), matched controls (n = 24), and unselected typically developing (n = 142) preschoolers completed sleep questionnaires. Preschoolers with SCA had significantly more sleep problems when compared to matched controls and the larger population. Snoring occurred at least one to two nights a week for 79% of the SCA group. This is compared with 25% of matched controls and 33% of larger population. Randomized controlled trials to improve sleep in young children with SCA already at-risk for cognitive dysfunction should be considered.

Keywords: early intervention; obstructive sleep apnea; sickle cell disease; sleep; sleep disordered breathing; snoring.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anemia, Sickle Cell / complications
  • Anemia, Sickle Cell / epidemiology*
  • Anemia, Sickle Cell / physiopathology*
  • Child
  • Child, Preschool
  • England / epidemiology
  • Female
  • Humans
  • Male
  • Parents*
  • Sleep Wake Disorders / epidemiology*
  • Sleep Wake Disorders / etiology
  • Sleep Wake Disorders / physiopathology*
  • Surveys and Questionnaires*