Transesophageal echocardiographic diagnosis of a WATCHMAN left atrial appendage closure device thrombus 10 years following implantation

Echocardiography. 2017 Jan;34(1):128-130. doi: 10.1111/echo.13413. Epub 2016 Nov 16.

Abstract

Left atrial appendage closure with the WATCHMAN device is an alternative to chronic oral anticoagulation for thromboembolic prophylaxis in atrial fibrillation patients. Left atrial device-related thrombus (DRT) has been described in the first year after implant with an incidence of ~6%. A 79-year-old man underwent WATCHMAN device placement in 2006. Routine protocol specified follow-up transesophageal echocardiograms (TEE) at 6 weeks, 6 months, and 1 year following implant showed no evidence for DRT or peri-device flow. A decade after device implant, the patient presented with severe symptomatic aortic stenosis and underwent repeat TEE, which revealed a 21 mm × 18 mm DRT on the LA aspect of the WATCHMAN device. He was prescribed apixaban 5 mg po BID. A TEE performed 111 days later demonstrated marked diminution in the DRT (9 mm in diameter). This case demonstrates that WATCHMAN DRT may occur late following implantation.

Keywords: Left atrial appendage thrombus; TEE.

Publication types

  • Case Reports
  • Video-Audio Media

MeSH terms

  • Aged
  • Atrial Appendage / diagnostic imaging
  • Atrial Appendage / surgery*
  • Atrial Fibrillation / surgery
  • Echocardiography, Three-Dimensional / methods*
  • Echocardiography, Transesophageal / methods*
  • Embolic Protection Devices / adverse effects*
  • Follow-Up Studies
  • Forecasting*
  • Heart Diseases / diagnosis*
  • Heart Diseases / etiology
  • Humans
  • Male
  • Prosthesis Failure
  • Thrombosis / diagnosis*
  • Thrombosis / etiology