We present high field magnetoresistance, Hall effect and thermopower measurements in the Ising-type ferromagnetic superconductor UCoGe. A magnetic field is applied along the easy magnetization c axis of the orthorhombic crystal. In the different experimental probes, we observed five successive anomalies at H≈4, 9, 12, 16, and 21 T. Magnetic quantum oscillations were detected both in resistivity and thermoelectric power. At most of the anomalies, significant changes of the oscillation frequencies and the effective masses have been observed, indicating successive Fermi surface instabilities induced by the strong magnetic polarization under a magnetic field.