Combine and Conquer: Double CTLA-4 and PD-1 Blockade Combined with Whole Tumor Antigen Vaccine Cooperate to Eradicate Tumors

Cancer Res. 2016 Dec 1;76(23):6765-6767. doi: 10.1158/0008-5472.CAN-16-2868.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • CTLA-4 Antigen / antagonists & inhibitors*
  • CTLA-4 Antigen / immunology
  • Cancer Vaccines / immunology
  • Cancer Vaccines / therapeutic use*
  • Colonic Neoplasms / immunology
  • Colonic Neoplasms / therapy*
  • Female
  • Humans
  • Lymphocytes, Tumor-Infiltrating / immunology
  • Mice
  • Ovarian Neoplasms / immunology
  • Ovarian Neoplasms / therapy*
  • Programmed Cell Death 1 Receptor / antagonists & inhibitors*
  • Programmed Cell Death 1 Receptor / immunology
  • Xenograft Model Antitumor Assays

Substances

  • CTLA-4 Antigen
  • CTLA4 protein, human
  • Cancer Vaccines
  • PDCD1 protein, human
  • Programmed Cell Death 1 Receptor