Abstract
Hepatitis E virus (HEV) infection causes acute liver disease, but severe infections are rare in immunocompetent patients. We describe a case of HEV infection in a previously healthy male trauma patient in France who received massive transfusions. Genotyping confirmed HEV in a transfused platelet pool and the donor.
Keywords:
HEV; blood transfusion; cholestasis; contaminated blood products; hepatitis E virus; immunocompetent; injury; jaundice; opportunistic infection; platelet transfusion; transfusion; trauma; viruses.
MeSH terms
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Adult
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Antibodies, Viral / blood*
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Antiviral Agents / therapeutic use*
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Blood Donors / ethics
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Blood Platelets / virology*
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Blood Transfusion / methods
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Cholecystitis, Acute / physiopathology
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Cholecystitis, Acute / surgery
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Cholecystitis, Acute / therapy
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Hepatitis E / diagnosis*
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Hepatitis E / drug therapy
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Hepatitis E / etiology
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Hepatitis E virus / genetics
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Hepatitis E virus / immunology
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Hepatitis E virus / isolation & purification
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Humans
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Male
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Platelet Transfusion / adverse effects*
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Respiratory Distress Syndrome / physiopathology
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Respiratory Distress Syndrome / therapy
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Ribavirin / therapeutic use*
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Ribs / injuries
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Shock, Septic / physiopathology
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Shock, Septic / therapy
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Spleen / injuries
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Splenectomy
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Splenic Rupture / surgery
Substances
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Antibodies, Viral
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Antiviral Agents
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Ribavirin