Identification of new geldanamycin derivatives from unexplored microbial culture extracts using a MS/MS library

J Antibiot (Tokyo). 2017 Mar;70(3):323-327. doi: 10.1038/ja.2016.143. Epub 2016 Dec 21.

Authors

Jae Kyoung Lee^{1

2}, Jae-Hyuk Jang¹, Dong-Jin Park³, Chang-Jin Kim³, Jong Seog Ahn¹, Bang Yeon Hwang², Young-Soo Hong¹

Affiliations

¹ Chemical Biology Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, Republic of Korea.
² College of Pharmacy, Chungbuk National University, Cheongju, Republic of Korea.
³ Microbial Resource Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.

PMID: 27999445
DOI: 10.1038/ja.2016.143

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Actinobacteria / growth & development
Actinobacteria / metabolism*
Benzoquinones / chemistry
Benzoquinones / isolation & purification*
Chromatography, High Pressure Liquid
Lactams, Macrocyclic / chemistry
Lactams, Macrocyclic / isolation & purification*
Tandem Mass Spectrometry

Substances

Benzoquinones
Lactams, Macrocyclic
geldanamycin