How to tackle antimalarial resistance?

EMBO Mol Med. 2017 Feb;9(2):133-134. doi: 10.15252/emmm.201607295.

Abstract

In the context of drug resistance, malaria is no exception. Even the latest artemisinins have started to lose their full efficacy in patients. Didier Leroy tells us about the strategies adopted by Medicines for Malaria Venture to reduce this terrible culprit.

MeSH terms

  • Antimalarials / pharmacology*
  • Antimalarials / therapeutic use
  • Artemisinins / pharmacology
  • Artemisinins / therapeutic use
  • Clinical Studies as Topic
  • Drug Resistance, Multiple / drug effects*
  • Drug Resistance, Multiple / genetics
  • Humans
  • Malaria, Falciparum / drug therapy*
  • Mutation
  • Plasmodium falciparum / drug effects*
  • Plasmodium falciparum / genetics
  • Plasmodium falciparum / isolation & purification
  • Quinolines / pharmacology
  • Quinolines / therapeutic use

Substances

  • Antimalarials
  • Artemisinins
  • Quinolines
  • artemisinin
  • piperaquine