[Haemostatic resuscitation in bleeding trauma patients]

Ugeskr Laeger. 2016 Dec 26;178(52):V06160450.
[Article in Danish]

Abstract

Trauma haemorrhage is a common reversible cause of death. Haemostatic resuscitation focuses on replacing the lost blood with transfusions equivalent to whole blood as early as possible. In Denmark, the optimal ratio for transfusions in massive bleeding is four packs of red blood cells, four packs of plasma and one pool of platelets (equal to ratio 1:1:1 in USA). Haemostatic resuscitation also includes a restricted use of crystalloids, early tranexamic acid, and a goal-directed transfusion therapy by using viscoelastic haemostatic assays to detect coagulopathy and the need for additional transfusions or pro-haemostatics.

Publication types

  • Review

MeSH terms

  • Antifibrinolytic Agents / therapeutic use
  • Blood Coagulation Disorders / therapy
  • Blood Transfusion / methods*
  • Critical Illness
  • Fluid Therapy
  • Hemorrhage / etiology
  • Hemorrhage / therapy*
  • Humans
  • Resuscitation / methods*
  • Thrombelastography
  • Time-to-Treatment
  • Tranexamic Acid / therapeutic use
  • Wounds and Injuries / complications

Substances

  • Antifibrinolytic Agents
  • Tranexamic Acid