A primary esophageal MALT lymphoma patient with Helicobacter pylori infection achieved complete remission after H. pylori eradication without anti-lymphoma treatment

Keiichi Moriya; Hideto Tamura; Kyoko Nakamura; Masaru Hosone; Koiti Inokuchi

doi:10.1016/j.lrr.2016.12.001

A primary esophageal MALT lymphoma patient with Helicobacter pylori infection achieved complete remission after H. pylori eradication without anti-lymphoma treatment

Leuk Res Rep. 2016 Dec 20:7:2-5. doi: 10.1016/j.lrr.2016.12.001. eCollection 2017.

Authors

Keiichi Moriya¹, Hideto Tamura¹, Kyoko Nakamura², Masaru Hosone³, Koiti Inokuchi¹

Affiliations

¹ Division of Hematology, Department of Medicine, Nippon Medical School 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan.
² Shin Akasaka Clinic, Tokyo, Japan.
³ Department of Pathology, Nippon Medical School Tama Nagayama Hospital, Tokyo, Japan.

Abstract

Primary esophageal lymphoma is an extremely rare disease. We report a 76-year-old woman with esophageal lymphoma who achieved remission after Helicobacter pylori (HP) eradication. Esophagogastroduodenoscopy (EGD) revealed a mass in the lower esophagus, and she was diagnosed with stage IE mucosa-associated lymphoid tissue (MALT) lymphoma. She rejected any anti-lymphoma treatment except for HP eradication. Follow-up EGD demonstrated the disappearance of the esophageal MALT lymphoma 2 months after HP eradication, and she remained in remission for more than 3 years. Our results demonstrate that HP eradication may be effective as initial therapy in primary esophageal MALT lymphoma patients with HP infection.

Keywords: Eradication therapy; Esophageal lymphoma; Helicobacter pylori; MALT lymphoma.

Publication types

Case Reports